Hm I see, do you have any monitoring tools that might be automatically hooking into your application? Or have you done a profiling session with Cassini before that may have ended badly (so that the profiler was not properly 'detached')?
Could you please:
-Download Process Explorer if you don't have it already - http://technet.microsoft.com/en-gb/sysi ... 96653.aspx
-Close down all instances of ANTS Performance Profiler running on your machine
-Start your application as normal
-Open Process Explorer, and look for the Cassini process
-Right click on the process, click Properties and then click the Environment tab.
-Look for the COR_ENABLE_PROFILING and COR_PROFILER variables and please let me know their values
That will hopefully give us an idea of what's currently attached!
Can I also check--when you get the original "Timed out waiting for port 2257 on 127.0.0.1 to become available" error, are there related errors in Event Viewer?