We are running an ASP.NET application and have upgraded to VS2013. When we use performance profiler now, the Application_Start event is firing for every single web request. This only happens when we are using the profiler and not when we are running the standard site in IIS on the same dev machine. This also did not happen prior to the VS2013 upgrade.
We have reverted the web app back to VS2012 but the problem is still occurring so possibly the problem was introduced in the 4.5.1 framework update that also got applied with VS2013.
This makes the profiler unusable for us as there are some hefty initialisations that occur during Application_Start, including database initialisation via NHibernate.